SJS and TENS are life-threatening reactions. If left untreated, they can result in death. Complications can include permanent blindness, dry-eye syndrome, photo phobia, lung damage, chronic obstructive pulmonary disease (COPD), asthma, permanent loss of nail beds, scarring of the esophagus
and other mucous membranes, arthritis, and chronic fatigue syndrome. Many patients pores
scar shut, causing them to retain heat. These are just some of the side-effects that have been
First and foremost, affected
persons must stop taking the offending drug immediately to prevent complications. Treatment
for SJS is good supportive care. Because patients literally burn from the inside out, burn, infectious disease, ophthalmology and dermatology teams are recommended. IV fluids and high calorie formulas are given to promote healing. Antibiotics are given when necessary to prevent secondary infections such as sepsis. Pain medications such as morphine are administered to make the patient as comfortable as possible. Most SJS patients can be managed in medical ICU or pediatric ICU. Patients with TENS should be treated in a burn unit.
Drug Reactions - A Serious Issue
Drug reactions are one of the leading causes of death in the United States. Yet, less than one percent are reported to the FDA, because there is no mandatory reporting system in effect for post marketing adverse drug reactions. Similarly, no one has an accurate count of the cases of SJS and TENS. Although SJS is listed as a rare disease, it may be more prevalent than previously thought.
The SJS Foundation
The SJS Foundation was founded
to be a resource to SJS victims
and their families. Our mission is to provide support services, and compile and distribute valuable information about SJS to the public and medical professionals regarding treatments and therapies that may prove beneficial to SJS sufferers. We work to promote awareness about the signs of SJS so that a quick diagnosis can be made and the offending agent stopped as soon as possible.
Reprinted with permission from The SJS Foundation.